Useful Scientific Links:

DMPK sites:

• International Society for the Study of Xenobiotics

• Drug Metabolism and Disposition

• FDA Guidance for Industry: In Vivo Drug Metabolism/Drug Interaction Studies

• Guidance for Industry Drug Metabolism/Drug Interaction Studies in the Drug Development Process: Studies In Vitro

• Basic Pharmacology v1.0 Part 1

• The Emerging Role of A.D.M.E. in Optimizing Drug Discovery and Design

• Cytochrome P450 isoform-specific in vitro methods to predict drug metabolism and interactions

• Cytochrome P450 System

• List of P450 Inhibiting Drugs

• ASPET Division for Drug Metabolism

• General Principles: Pharmacokinetics

• A Dictionary of Terms Used in Drug Metabolism

• In Vitro Approaches to Human Drug Metabolism

• A First Course in Pharmacokinetics and Biopharmaceutics

Pharmaceutics / Formulations sites:

• Amorphous API in Preclinical Studies-Nagapudi

• Development of Enabling Formulations_Nadkarni

• Developability & early development strategies-Neervannan

• 2006_ExpOpinion_Preclin Form_SN

Physicochemical Property sites:

• Physicochemical Characteristics of Drug Molecules

• A guide to Log P and pKa measurements and their use

• PKa list

• Bordwell pKa Table (Acidity in DMSO)

• Cell Permeability Assays

• PAMPA

•  

Mass spectrometry sites:

• American Society for Mass Spectrometry

• A History of Mass Spectrometry (Scripps)

• Academic Mass Spectrometry web sites

• SpectroscopyNow

• Little Encyclopedia of Mass Spectrometry

• Forum of Scientific Education-MS & HPLC-(a great site by Shula Levin!!!)

• Interpreting Electrospray Mass Spectra

• An Introduction to Mass Spectrometry (University of Leeds)

• Mass Spectrometry and Biotechnology Resource (IonSource.com)

• Web Diamonds (IonSource.com)

• FTMS Tutorial (IonSpec)

• Mass Spectrometry Consultants and Contract Labs

• Mass Spectrometry Forum

MS Utilities and calculators:

• University of Alberta

• Isotope patterns calculator

• Exact Mass Calculator

Chromatography sites (list provided by Michael Dong)

• Liquid Chromatography (book by R.P.W.Scott)

• The Mechanism of Chromatographic Retention (book by R.P.W.Scott)

• Reverse Phase HPLC Basics for LC/MS

• Online Guide to Chiral HPLC

• LC.GC magazine

• HPLC training, LC Resources

• Basic HPLC from SHU 

• Journal of Chromatography A

• HPLC tutorial

• Chromatography resources

• A guide to HPLC

• On-line and training resources

NMR sites:

• Nuclear Magnetic Resonance (spincore.com)

• NMR page of SpectroscopyNow.com

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Proteomics sites (list provided by Kenneth Straub)

• http://www.proteome.org/

• http://www.hupo.org/

• Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University

• Mascot (search engine for identifying proteins from mass spectrometry data)

• Delta Mass

• Protein Prospector of UCSF

• Protein Modifications for Mass Spectrometry

Capillary Electrophoresis sites:

• Capillary Electrophoresis Primer

Instrument trading sites:

• Grizzly Analytical Biotech Lab Equipment

• LabTrader Scientific Equipment

• Triad Scientific

• Scientific Asset Management

• Used-line.com

• McKinley Scientific

Independent Instrument Services:

• Full Spectrum Analytics, Inc.